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Buy Minipress (Prazosin Hydrochloride) sympatholytic and antiadrenergic agent
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MINIPRESS (PRAZOSIN HYDROCHLORIDE): USE IN SPECIAL POPULATIONS

Pregnancy

Pregnancy Category C

Prazosin HCl (Minipress) has been shown to be associated with decreased litter size at birth, 1, 4, and 21 days of age in rats when given doses more than 225 times the usual maximum recommended human dose. No evidence of drug-related external, visceral, or skeletal fetal abnormalities were observed. No drug-related external, visceral, or skeletal abnormalities were observed in fetuses of pregnant rabbits and pregnant monkeys at doses more than 225 times and 12 times the usual maximum recommended human dose, respectively.

The use of prazosin and a beta-blocker for the control of severe hypertension in 44 pregnant women revealed no drug-related fetal abnormalities or adverse effects. Therapy with prazosin was continued for as long as 14 weeks.

Prazosin has also been used alone or in combination with other hypotensive agents in severe hypertension of pregnancy by other investigators. No fetal or neonatal abnormalities have been reported with the use of prazosin.

There are no adequate and well controlled studies which establish the safety of Minipress capsules in pregnant women. Prazosin HCl (Minipress) should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and fetus.

Nursing Mothers

Minipress (Prazosin) has been shown to be excreted in small amounts in human milk. Caution should be exercised when Minipress (Prazosin HCl) is administered to a nursing woman.

Usage in Children

Safety and effectiveness of Prazosin (Minipress) capsules in children have not been established.

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